Semagloutide nplej hmoov

 

Semagloutide nplej hmoovyog lub cev daim ntawv ntawm semaglutide API, feem ntau yog siv los ua qhov ncauj lossis txhaj kev npaj.

 

 

Cov khoom	Cov lus qhia	Qho kawg
Kev tshwm sim	Dawb lossis yuav luag dawb xoob hmoov	Dawb xoob hmoov
So	Dawb soluble hauv dej; Firstly, ntxiv cov dej freshly thiab txias kom ua kom muaj cov tshuaj kom haum rau 3.5 nrog rau 0.05m.Qhov kev daws teeb meem yuav tsum yog 3.0 thiab ua kom haum 30 thib ob lub rang ntawm pH 3.0 mus rau 5.5.	Ntuas
Kev kho tshiab kev sib hloov [a] ²D	- 15.0℃rau-10.0℃(cov tshuaj lom neeg thiab sodium ion-pub dawb} mg, h₂o)	-13.9 Qib
Kev cim los ntawm HPLC	Kev tuav lub sijhawm ntawm tus thawj coj ntawm qhov ntsuas ntsuas sib raug zoo nrog cov lus qhia, raws li tau txais hauv cov assay.	Ntuas
Molecular Ion Mass	4113.58±1.0	Ntuas
Amino acid exagect	ASP: 0.9-1.1 Ser: 2.7-3.3 GLU: 4.5-5.5 Gly: 3.6-4.4 Nws: 0.9-1.1 AG: 1.8-2.2 Thr: 1.8-2.2 Ala: 2.7-3.3 AIB: 0.9-1.1 Tyr: 0.9-1.1 Val: 1.8-2.2 Lys: 0.9-1.1 Eile: 0.9-1.1 Leu: 1.8-2.2 Phe: 1.8-2.2 AEEA: Yuav tsum kuaj pom	1.0 3.0 5.0 4.0 1.0 2.0 2.0 3.0 1.1 1.0 1.9 1.0 1.0 2.0 2.0 Ntuas
pH	7.0-9.0	7.5
Cov ntsiab lus dej (KF)	Nmt 8.0%	5.3%
Tshuaj Clarity thiab Xim	Ntshiab thiab tsis muaj xim	Ntuas
Lwm yam tshuaj (HPLC)	Impurity a: nmt0.3% IF IFGURRURUR D: NMT0.3% IFRISURRURRURRURING E: NMT 0.1% Ib tug neeg impurity: nmt 0.1% Tag nrho cov impurities: nmt1.5%	N.D N.D N.D 0.06% 0.3%
Lwm yam tshuaj (HPLC)	Impurity B: NMT0.1%% Impurity C: NMT0.1%%	0.02% 0.05%
Sodium ion	1.5%-4.0%	2.2%
Siab molecular protein	Nmt 0.5%	0.03%
Residual Hnyav	Methylene chloride NMT 600PPM Acetonitrile NMT 410PPPM Methanol NMT 3000PPM Dmf nmt880ppm Isopropyl ether nmt 5000ppm Isopropanol nmt 5000ppm	N.D 12Ppm N.D N.D N.D N.D
Bacterial endotoxins	Nmt 10eu / mg	Ntuas
Microbial txwv	Tamp nmt 200cfu / g Tymc nmt 100cfu / g	<10cfu/g <10cfu/g
Groud Group ions	Trifluoroacetate Ion NMT0.1% Phosphate Ion NMT 0.1% Chloride ion nmt 0.1% Acetate Ion NMT 0.1%	N.D N.D 0.01% N.D
Lam xav	95.0% -} 105.0% (xam nrog siv rau cov khoom siv anhydrous thiab pub dawb.	100.0%
Chaw ntim khoom	Khaws cia rau hauv lub thawv kaw ntom nti, tiv thaiv los ntawm lub teeb, khw ntawm qhov kub ntawm-20 ± 5 degree.
Xaus: Cov khoom no ntawm cov khoom ua raws li cov qauv kev lag luam.

 

 

1. Kev kho mob hom ntshav qab zib hom 2

• Raws li GLP-1 tus receptor agonist, nws siv cov ntshav qab zib txo los ntawm kev tso pa insulin tso tawm thiab ua rau muaj kev tso tawm glucon.
• Nws kuj tseem tuaj yeem txo cov kev pheej hmoo ntawm kev nyab xeeb thiab kev pheej hmoo ntawm myocardial infarction nyob rau hauv cov neeg mob ntshav qab zib.

 

2. Cov khoom xyaw
Semagloutide nplej hmoovYuav tsum tau ua tiav los ntawm cov tshuaj uas tsim khoom lossis txhaj tshuaj thiab yuav tsum tsis txhob coj ncaj qha.

 

3. Lub cev yuag poob
Ntawm cov koob tshuaj ntau dua, nws tuaj yeem pab tau qhov hnyav tswj hwm hauv cov rog (BMI ntau dua los yog sib npaug ntawm 27 thiab comorbidities) cov neeg mob los ntawm kev nce kev lom zem thiab ncua lub plab.

 

 

1. Cov kev mob tshwm sim los:

• Kev cuam tshuam hauv plab: xeev siab, ntuav, raws plab, mob plab, thiab cem quav, feem ntau tshwm sim thaum pib kev kho mob.
• Kev pheej hmoo ntawm hypoglycemia: soj ntsuam cov ntshav cov ntshav qab zib, tshwj xeeb tshaj yog thaum siv nrog cov tsiaj txhu lossis insulin.

 

2. Tsawg tab sis kev mob tshwm sim loj:

• Panceitis: Mob plab mob hnyav thiab ntuav yuav tsum tau kho mob sai sai.
• Thyroid Tumor yuav:Semagloutide nplej hmoovTej zaum yuav nce qhov kev pheej hmoo ntawm cov thyroid c -} cov qog cell. Siv yog contraindicated nyob rau hauv cov neeg mob uas muaj lub qog nqaij hlav me me carcinoma lossis ntau qhov endocrine noplyries.

 

3. Lwm cov kev pheej hmoo muaj peev xwm:
Cholelithiasis, wordering lub raum muaj nuj nqi, thiab retinopathy.

 

4. Confaindications:

Cov khoom no yog contraindicated rau cov neeg mob lossis tsev neeg zaj keeb kwm ntawm cov qog ntshav plab, nquag pancreatitis, kev xeeb tub / lactation, lossis lub txim hnyav.

 

 

Peb cov khoom tau ntawv pov thawj Haccp, Halal, thiab kosher. Peb lub tuam txhab tau dhau ISO22000 Kev Tswj Xyuas Zoo Zoo. Peb tuaj yeem muab cov neeg siv khoom nrog cov khoom uas lawv xav tau thiab muab kev thauj mus los yooj yim thiab yooj yim. Piv txwv li: huab cua thauj, thauj khoom hiav txwv

 

Peb muaj cov neeg ua lag luam tshaj lij kev lag luam los txuas lus nrog koj kom nkag siab koj cov kev xav tau thiab nkag siab txog cov khoom. Muaj cov kws tshaj lij ntawm email, koj tuaj yeem tso cov lus txhua lub sijhawm, thiab peb yuav teb tau sai li sai tau peb.Email: info@fruiterco.com.

 

 

Cim npe nrov: SEMAGLUTIDE Hmoov nplej, Tuam Tshoj semaglutide RAW hmoov tuam ntxhab, lwm tus neeg, Hoobkas