Dab tsi yog qhov txawv ntawm NAD + thiab NADH?

 

Nicotinamide adenine dinucleotide, hu ua NAD. NAD los ntawm ob hom: NAD + thiab NADH.

 

NAD yog qhov tseem ceeb rau kev ua haujlwm zoo ntawm txhua lub cell hauv lub cev, xws li DNA kho, metabolism, thiab lwm yam. Nws ua raws li "tus pab molecule", activating enzymes lub luag hauj lwm rau hloov cov as-ham rau hauv usable zog. Yog tias tsis muaj qib NAD txaus, cov txheej txheem cellular kaw, ua rau muaj ntau yam teeb meem kev noj qab haus huv.

 

NAD + thiab NADH tsim ib khub redox, txhais tau hais tias lawv yog cov oxidized thiab txo cov ntaub ntawv ntawm tib molecule. Hauv cov tshuaj tiv thaiv redox, NAD + poob ib qho hluav taws xob thiab dhau los ua NADH, thaum NADH tau txais ib qho hluav taws xob thiab rov qab mus rau NAD+. Qhov kev hloov hluav taws xob no tseem ceeb heev rau kev tsim hluav taws xob thiab tswj cov cellular redox tshuav nyiaj li cas.

 

 

1. Cov qauv molecular sib txawv
Beta nicotinamide adenine dinucleotideyog daim ntawv oxidized, uas txhais tau hais tias nws tau poob electrons thiab muaj ib tug zoo nqi. NADH yog daim ntawv txo, uas tau txais electrons thiab tsis muaj nqi.

 

 

2. Oxidation thiab txo qis
Qhov sib txawv ntawm cov qauv tseem ceeb ntawm daim ntawv oxidized (NAD +) thiab daim ntawv txo (NADH) ntawm NAD yog muaj ib qho ntxiv hydrogen atom thiab ob lub electrons ntxiv hauv NADH. Qhov kev hloov kho no neutralizes tus nqi zoo ntawm NAD + nicotinamide nplhaib, hloov nws cov kev teeb tsa spatial thiab kev sib cuam tshuam.

 

3. Kev ua haujlwm lom neeg
NAD + thiab NADH yog cov tseem ceeb ntawm cov tshuaj tiv thaiv redox, uas yog lub hauv paus rau cellular zog tsim. Ntxiv rau lawv lub luag haujlwm hauv kev tsim hluav taws xob, NAD thiab NADH tau koom nrog ntau txoj hauv kev ntawm tes taw qhia, xws li kev qhia gene, kho DNA, thiab kev ntxhov siab.

 

4. Ratio of NAD+ to NADH
Qhov piv ntawm NAD + rau NADH yog qhov cim tseem ceeb ntawm kev noj qab haus huv ntawm tes, cuam tshuam rau ntau yam txheej txheem metabolic thiab biochemical. Qhov piv ntawm NAD no tsis tsuas yog qhia txog lub peev xwm ntawm tes los tsim lub zog, tab sis kuj tseem ua lub luag haujlwm tseem ceeb hauv kev tswj hwm redox tshuav nyiaj li cas, kho DNA, thiab tag nrho cov cellular muaj nuj nqi.

 

Ib qho piv txwv ntawm NAD + rau NADH, xws li 3.1 txog 3.6, feem ntau yog lub cim ntawm cov hlwb noj qab haus huv, qhov twg NAD + hauv nws daim ntawv oxidized plays lub luag haujlwm tseem ceeb hauv coenzyme hauv cov tshuaj tiv thaiv redox. Hauv cov tshuaj tiv thaiv no,NAD+txhawb nqa oxidation ntawm cov as-ham, ua rau kev tsim cov ATP, lub cell lub ntsiab lub zog.

 

 

1. Kev tsim hluav taws xob

NAD + yog ib qho ntawm cov khoom tseem ceeb hauv kev ua pa ntawm tes, pab hloov cov zaub mov rau hauv lub zog siv tau los ntawm cov tshuaj tiv thaiv redox. Thaum lub sijhawm ua haujlwm no, NAD + lees txais cov khoom siv hluav taws xob thiab raug txo rau NADH.

 

2. kho DNA

NAD + nicotinamide adenine dinucleotidelub substrate ntawm PARP (poly ADP{0}}ribose polymerase), uas yog qhov tseem ceeb rau kev tshawb nrhiav thiab kho DNA puas.

 

3. Ua kom lub neej ntev

NAD + tseem yog ib qho tseem ceeb substrate rau Sirtuins tsev neeg cov proteins. Cov proteins no muaj feem xyuam rau kev ua neej ntev thiab tswj kev mob thiab kev ntxhov siab.

 

4. Cell signaling

NAD + kuj tseem koom nrog ntau yam ntawm lwm cov xov tooj ntawm tes taw qhia txoj hauv kev, suav nrog kev tswj hwm circadian atherosclerosis, kev tiv thaiv kab mob, thiab kev tiv thaiv neuroprotection.

 

5. Anti-kev laus

Thaum muaj hnub nyoog nce, lubnicotinamide adenine dinucleotide hmoovtheem hauv tib neeg lub cev yuav txo qis. Kev tuav lossis nce qib NAD + yog suav tias yog los pab ncua kev laus - cuam tshuam txog lub cev tsis muaj zog.

 

6. Txhawb kev noj qab haus huv

Kev tshawb fawb qhia tau hais tias NAD + pab tswj kev mob plawv, txhim kho cov leeg nqaij, txhim kho kev tiv thaiv kab mob, thiab lwm yam.

 

 

Peb cov hmoov NAD yog qhov tshwj xeeb zoo thiab tsim nyog rau kev xa tawm mus rau lub tebchaws xws li Lub Tebchaws Yelemees, Tebchaws Meskas, Romania, Canada, thiab Bulgaria. Peb zoo siab txais tos thib peb -kev kuaj xyuas thiab lav tag nrho tom qab- kev txhawb nqa muag yuav tsum muaj teeb meem zoo tshwm sim.

 

 

 

Fruiterco tuaj yeem muab txoj kev xa khoom zoo thiab yooj yim rau cov khoom uas cov neeg siv khoom xav tau. Piv txwv li: huab cua, hiav txwv, nthuav qhia, koj tuaj yeem so kom paub tseeb tias cov khoom lag luam teeb meem zoo thaum thauj.

 

Peb muaj cov neeg ua haujlwm tshaj lij kev lag luam sib txuas lus nrog koj txog koj cov khoom xav tau thiab kev nkag siab. Muaj kev tshaj lij mailbox system, koj tuaj yeem tawm lus txhua lub sijhawm, peb yuav teb sai li sai tau thaum peb pom. Yog tias koj muaj cov khoom xav tau, koj tuaj yeem tawm lus txhua lub sijhawm thiab peb yuav teb sai li sai tau thaum peb pom. Tiv tauj peb kom paub meej ntxiv:Email: info@fruiterco.com.