Dab tsi yog Cov txiaj ntsig thiab Kev Siv Isatis Tinctoria Extract Ua Lub Ntuj Pigment?

 

Isatis tinctoria extractyog ib tsob nroj extract tau los ntawm nplooj, aerial qhov chaw, los yog lwm yam tsim nyog qhov chaw ntawm lub isatis tinctoria L. cog los ntawm dej extraction, cawv extraction, los yog lwm yam txheej txheem txheem.

 

Los ntawm phytochemical foundations, ib qho ntawm cov yam ntxwv zoo tshaj plaws ntawm isatis tinctoria yog nws cov ntsiab lus ntawm indoxyl glycosides. Los ntawm enzymatic hydrolysis thiab oxidation, cov precursors no ua rau indole tebchaw xws li indigo thiab indirubin. Kev tshawb fawb qhia tau hais tias isatis tinctoria tsis ncaj qha synthesize mature indigo; Hloov chaw, nws ua ntej tsim cov khoom ua ntej sib xws, uas tom qab tau hloov pauv hauv cov xwm txheej ntawm cov ntaub so ntswg puas thiab oxidation.

 

Cov khoom xyaw nquag:

 

1. Indigo

2. Indirubin

3. Tryptanthrin

4. Isatin

5. Flavonoids, lignans, thiab lwm yam phytochemicals

 

 

Nyob rau hauv xyoo tas los no, kev tshawb fawb ntawm Isatis hom tau nthuav dav tshaj li cov tshuaj botany thiab natural dye kev tshawb fawb rau hauv thaj chaw xws li cog tshuaj, tshuaj dermatology, plab hnyuv, thiab kev tshawb fawb ntawm natural bioactive compounds.

 

Ib txoj kev tshawb fawb luam tawm nyob rau hauv * Suav Tshuaj * hauv 2022 tau tshawb xyuas qhov cuam tshuam ntawm aqueous extract ntawm isatis tinctoria hauv DNCB-induced atopic dermatitis nas qauv thiab hauv HaCaT keratinocytes. Txoj kev tshawb no muab cov pov thawj kev sim txuas cov aqueous extract ntawm isatis tinctoria rau kev hloov kho ntawm daim tawv nqaij o.

 

Tsis tas li ntawd, tshuaj xyuas cov khoom hais txog Isatis hom thiab Indigo Naturalis tseem tsom mus rau cov khoom tseem ceeb xws li indirubin, indigo, isatin, thiab tryptanthrin.

 

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias Indigo Naturalis tsis yog lub ntsiab lus nrog isatis tinctoria extract. Indigo Naturalis tuaj yeem muab tau los ntawm ntau qhov chaw cog-xws li isatis tinctoria, Isatis indigotica, Persicaria tinctoria, thiab Strobilanthes cusia- txhais tau hais tias qhov sib txawv tseem ceeb ntawm cov tshuaj muaj pes tsawg leeg thiab cov qauv zoo yuav muaj nyob ntawm cov khoom.

 

Qhov no qhia txog vim li cas cov kws tshawb fawb thiab cov neeg tsim khoom lag luam yuav tsum ua tib zoo xav txog cov khoom siv raw thiab qib ntawm kev tsim qauv thaum xaiv isatis tinctoria extract.

 

 

1. Anti- mob

Inflamation-Txoj kev taw qhia txog kev ua haujlwm sawv cev rau thaj chaw tseem ceeb ntawm kev tshawb fawb txog cov khoom siv ntawm isatis hom.

 

Cov kev tshawb fawb uas twb muaj lawm qhia tau hais tias cov tshuaj indole tshwj xeeb tuaj yeem cuam tshuam cov teeb liab sib txuas xws li NF{{0}κB, MAPK, thiab TLR4/MYD88.

Kev tshuaj xyuas xyoo 2024 tau sau tseg ntxiv txog cov txheej txheem muaj peev xwm ntawm isatis tinctoria nyob rau hauv cov ntsiab lus ntawm cov kab mob plab hnyuv, qhia txog nws txoj kev tswj hwm txoj hauv kev suav nrog NF{{1}κB, NLRP3 / IL-1 , TLR4 / MYD88 / NF-κB, thiab MAPK.

 

Rau kev loj hlob ntawm cov nroj tsuag -raws li cov khoom xyaw, qhov no txhais tau hais tias lub hauv paus kev tshawb fawb txog kev siv tshuab zoo rau qee yam muaj txiaj ntsig muaj nyob hauv *Isatis* hom.

 

2. Kev tswj lub cev tiv thaiv kab mob

Nyob rau hauv xyoo tas los no, aryl hydrocarbon receptor (AhR) tau tshwm sim los ua ib qho tseem ceeb hauv kev tshawb fawb ntawm ntuj indole tebchaw.

 

Qee cov nroj tsuag- muab tau los ntawm indole tebchaw tuaj yeem cuam tshuam nrog AhR-txog kev sib txuas lus; AhR, nyob rau hauv lem, plays lub luag hauj lwm nyob rau hauv kev tiv thaiv kab mob, barrier muaj nuj nqi, thiab inflammatory teb.

 

Yog li ntawd, indole derivatives los ntawm hom isatis tau dhau los ua tus neeg sib tw tseem ceeb rau kev tshawb fawb txog yuav ua li cas cov nroj tsuag ntuj tsim tswj kev tiv thaiv kab mob thiab kev tiv thaiv- ntsig txog kev ua haujlwm.

 

3. Muaj peev xwm tiv thaiv antioxidant

Kev ntxhov siab oxidative txuas nrog ntau yam kev lom neeg, nrog rau kev mob, kev ua haujlwm ntawm daim tawv nqaij, thiab kev puas tsuaj ntawm tes. Cov kev tshawb fawb tam sim no qhia tias cov khoom xyaw nquag tau los ntawm hom Isatis tuaj yeem cuam tshuam oxidative kev ntxhov siab xws li SOD, GSH, thiab MDA. Txawm li cas los xij, feem ntau ntawm cov pov thawj tam sim no yog muab los ntawm kev tshawb fawb ntawm tes thiab tsiaj txhu.

 

 

1. Kho kom zoo nkauj Sector

Qhov no yog ib qho tseem ceeb ntawm daim ntawv thov rau * Isatis tinctoria * extract. Muab nws cov nroj tsuag ntuj tsim thiab muaj cov phytochemical constituents xws li indoles thiab flavonoids, nws muaj peev xwm ua hauj lwm raws li ib tug active botanical muaj nyob rau hauv:

• ntsej muag cream;
• Serums;
• Tshuaj pleev ib ce;
• Lub ntsej muag lub ntsej muag;
• Cov tshuaj ntxuav tes;
• Cov khoom siv kho lub cev;
• Cov khoom siv tawv taub hau;
• Cog -raws li formulations.

 

2. Skincare R&D

Aqueous extracts ntawm isatis tinctoria tau kawm nyob rau hauv tsiaj thiab HaCaT cell qauv hais txog daim tawv nqaij o, tsim ib lub hauv paus rau kev tshawb fawb ntawm daim tawv nqaij ntxiv.

 

3. Ntuj Pigments thiab Dyes

Cov khoom lag luam classic tshaj plaws ntawm isatis tinctoria nyob rau hauv nws txoj kev siv los ntawm ntuj indigo. Nyob rau hauv xyoo tas los no, nrog rau kev loj hlob ntawm cov xim ntuj thiab cov khoom siv ruaj khov, nws tau rov tshwm sim dua los ua qhov chaw ntawm ntuj indigo.

 

Ib txoj kev tshawb fawb xyoo 2022 tau tshuaj xyuas qhov kev hloov pauv ntawm isatis tinctoria- los ntawm nws lub luag haujlwm los ua cov xim nruab nrab rau nws qhov chaw hauv kev lag luam niaj hnub ntuj indigo- ceeb toom tias kev lag luam rau cov xim ntuj tau txhawb nqa kev txaus siab rau kev cog qoob loo ntawm isatis tinctoria thiab kev tsim cov indigo.

 

4. Khoom noj khoom haus

Ntau yam phytochemicals pom nyob rau hauv Isatis hom tau raug tshawb xyuas rau lawv cov tshuaj tiv thaiv -inflammatory, antioxidant, thiab immunomodulatory zog. Yog li ntawd, los ntawm qhov kev xav ntawm kev tsim cov khoom siv raw, cov nroj tsuag no muaj peev xwm rau kev tshawb fawb ntxiv nrog rau kev tshuaj xyuas, kev cais tawm, kev tsim qauv, thiab kev tsim cov khoom xyaw bioactive cog.

 

Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias qhov tsim nyog ntawm cov nroj tsuag rau kev siv zaub mov yuav tsum tau txiav txim siab raws li lub hom phiaj kev lag luam, cov khoom siv cog tshwj xeeb, cov txheej txheem rho tawm, thiab kev ntsuas kev nyab xeeb; Tsis tas li ntawd, cov nroj tsuag tsis muaj cov khoom kho mob.

 

 

Piv nrog rau cov qauv botanical hmoov, standardized isatis tinctoria extract yog zoo dua haum rau niaj hnub khoom tsim thiab kev loj hlob.

1. Paub meej botanical Source: Muab los ntawm isatis tinctoria L., tso cai rau kev tsim kom muaj ib tug meej botanical tus kheej rau cov khoom siv raw.

 

2. Muaj Cov Indole Phytochemicals Distinctive: Cov tshuaj xws li indigo, indirubin, isatin, thiab tryptanthrin muab cov txiaj ntsig tshwj xeeb rau kev tshawb fawb phytochemical.

 

3. Kev Tshawb Fawb Txog Kev Tshawb Fawb: Ib lub cev dav dav ntawm kev tshawb fawb muaj nyob rau isatis tinctoria, spanning thaj chaw los ntawm ntuj pigments thiab phytochemistry mus rau kev tshawb fawb txog kev mob, kev noj qab haus huv ntawm daim tawv nqaij, thiab cellular signaling.

 

4. Ntau yam khoom siv: Tsim nyog rau kev tsim khoom thoob plaws ntau pawg, suav nrog cov khoom siv ntuj tsim, cov xim ntuj, kev tu tawv nqaij, kev tshawb fawb antioxidant, thiab cov khoom xyaw cog qoob loo.

 

5. Dual Value (Natural Pigment & Bioactive Ingredient): Cov yam ntxwv tseem ceeb no txawv ntawm isatis tinctoria los ntawm ntau cov khoom siv botanical.

 

 

Fruiterco yog lub tuam txhab xa tawm uas feem ntau tsim cov khoom cog, cov khoom noj khoom haus raw khoom, thiab cov khoom siv tshuaj pleev ib ce. Lub tuam txhab muaj 20+ kev pabcuam tom qab- pab pawg muag khoom.

 

Peb cov khoom raug muag rau North America, Europe, Australia, South America thiab Asia. Peb cov khoom tau dhau los soj ntsuam zoo thiab tseem txhawb cov neeg siv khoom rov- tshuaj xyuas. Peb yog cov chaw tsim khoom thiab chaw tsim khoom ntawm cov taum liab hmoov. Yog koj xav tauYuav Isatis Tinctoria Extract, thov hu rau peb:Email: info@fruiterco.com.

 

 

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2. Choque E, Martin P. Kev Kawm ntawm Woad (Isatis tinctoria L.)-Extracted Indoxyl Precursors Conversion into Dyes: Influence of the Oxidative Media on Indigo Recovery Yields and Indigotin/Indirubin Ratio Measured by HPLC-DAD Method. Molecules . 2024; 29(20):4804. DOI: 10.3390 / molecules 29204804 ib.
3. Kim H, Jeong S, Kim SW, et al. Indigo Naturalis nyob rau hauv mob plab hnyuv kab mob: cov txheej txheem ntawm kev ua thiab kev pom los ntawm kev sim tshuaj. Phau ntawv Journal of Pharmacopuncture. 2024;27(2:59–69. DOI: 10.3831/KPI.2024.27.2.59.
4. Xu Y, Lin C, Tan HY, Bian Z X. Ob tug -edged ntaj nyhuv ntawm indigo naturalis. Khoom noj khoom haus thiab tshuaj toxicology. 2024; 185:114476. DOI: 10.1016/j.fct.2024.114476.
5. Indigo naturalis yog ib qho tshuaj muaj peev xwm hauv kev kho mob ulcerative colitis: kev tshuaj xyuas cov pov thawj tam sim no . 2024. Kev Tshawb Fawb Txog Kev Kho Mob tam sim no thiab kev xav.
6. Min SY, Kim TY, Kim JH, et al. Inhibitory nyhuv ntawm Isatis tinctoria L. dej extract ntawm DNCB-induced atopic dermatitis nyob rau hauv BALB/c nas thiab HaCaT hlwb. Suav Tshuaj . 2022; 17:66.
7. Isatis indigotica: kev tshuaj xyuas ntawm phytochemistry, kev ua haujlwm tshuaj thiab kev siv tshuaj kho mob. Phau ntawv Journal of Pharmacy and Pharmacology. 2021;73(9):1137–1154.
8. Kev Tshawb Fawb Txog Kev Tshawb Fawb Txog Tshuaj, Pharmacokinetics, Pharmacology, Kev Siv Tshuaj Kho Mob, Cov Txheej Txheem Tsis Zoo, thiab Kev Tswj Xyuas Zoo ntawm Indigo Naturalis. 2021.
9. Isatis tinctoria L. (Woad): Kev Tshawb Fawb Txog Nws Cov Botany, Ethnobotanical Siv, Phytochemistry, Biological Activities, thiab Biotechnological Studies. Molecules . 2020.